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It’s Time to EMPOWER

Our Efforts to Help Close the PCI Outcomes Gap in Calcified Lesions

Underdiagnosed. Under‑represented. Underwhelming outcomes. We know that there is much work to be done to bridge the PCI inequality gap between females and males. That’s why we’re committing our expertise, clinical focus and technological advances to do everything we can to narrow the gap.

New Shockwave IVL Publication Shows Similar Outcomes in Women and Men.

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Shockwave Launches EMPOWER CAD, the First Prospective, Female-Only Study of Coronary Interventions, in Collaboration with Female Leaders

Alexandra Lansky

Early retrospective analyses have suggested that coronary IVL can potentially bridge the disparity in clinical outcomes between sexes, however the studies only included a limited number of females with strict inclusion criteria. Information that will be gathered in EMPOWER CAD will be immensely valuable, as it will provide more robust data with longer-term outcomes in a larger, all-comers patient cohort to determine whether coronary IVL should be considered the front-line calcium modification approach in female patients.

When it comes to coronary artery disease (CAD), females are often under investigated, under treated and have less favorable outcomes than males due to a variety of different factors. Previous reports with atherectomy have shown that females with calcified CAD are more susceptible to adverse procedural outcomes compared to males. Despite often being more challenging to treat, female patients are under-represented in published data, and there have been no dedicated prospective studies performed on this population. EMPOWER CAD will be an extremely valuable study to better inform interventional cardiologists on the optimal treatment strategy for these complex patients.

Margaret McEntegart
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The First EMPOWER CAD Female Case: Image Guided Lithotripsy

Coronary IVL Data in Females vs. Males

Sex-specific OCT characterization of Intravascular Lithotripsy for Treatment of Calcified Coronary Lesions

Pooled Analysis of Disrupt CAD OCT Sub-studies

The largest sex-specific OCT analysis demonstrates excellent stent expansion and MSA post-IVL with impressive procedural safety in both women and men.

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Sex-specific 1-year Outcomes in Coronary Intravascular Lithotripsy

Patient-level Pooled Analysis of Disrupt CAD Studies

The long-term analysis of coronary IVL finds sustained positive clinical outcomes with excellent safety in both women and men at one year.

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Female IC leaders discuss takeaways from SCAI 2022

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Coronary IVL: First Line Therapy for Female Patients?

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Shockwave IVL Coronary Studies Demonstrate Excellent PCI Outcomes in Both Women and Men at One Year

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Shockwave Sponsors Calcium-focused SCAI Early Career Research Grant

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Equality With Dr. Alexandra Lansky: Coronary IVL Outcomes by Sex

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The Educational Symposium on Myocardial Infarction in Women at ACC '22 is now available online

Watch Here

Disrupt PAD III OS Male vs. Female Data

Leveling the Playing Field with Sound

Coronary IVL SCAI 2022 Symposium

How It Started vs. How It’s Going: Coronary Calcium Modification Outcomes in Men vs. Women

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The Path Forward From Inequality to Equals

Some of us know the data. Some don’t. The question once you do is where we go from here to bridge the inequality gap between females and males? To help address this question, here is a great discussion hosted by SCAI Conversations in Interventional Cardiology with Drs. Alexandra Lansky, J. Dawn Abbott, Jennifer Tremmel, Roxana Mehran, and Suzanne Baron on the recently JSCAI published “Expert Consensus on Sex Specific Considerations in Myocardial Revascularization.”

SCAI’s “Expert Consensus on Sex Specific Considerations in Myocardial Revascularization”

JSCAI recently published new guidelines, which highlight disparities between females and males in coronary disease, guides future research priorities and suggests IVL as a potential first-line therapy in females with calcified lesions.

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Partnering with Others

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The SCAI-WIN mission is to foster professional development, education, collaboration, and research by and on behalf of women in interventional cardiology and their patients.

Shockwave is happy to be one of the SCAI-WIN CHIP Fellowship supporters. Congratulations to Dr. Njambe Mathenge!

Njambi Mathenge

Njambi Mathenge, MD, MPH


Fellowship Award


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Women as One logo

The Women As One mission is to promote talent in medicine, providing women physicians with unique professional opportunities. By doing this, Women As One aims to build a more inclusive, diverse and just workforce in medicine.

The Lancet Women and Cardiovascular Disease Commission logo

The Lancet Women in Cardiovascular Disease Commission, led by Dr. Roxana Mehran, summarizes existing evidence and identifies knowledge gaps in research, prevention, treatment, and access to care for women. It furthermore outlines ambitious new recommendations with a clear focus on reducing the global burden of cardiovascular disease in women by 2030.

European society of cardiology logo

Shockwave is happy to support EAPCI Fellowship education grant programme. Congratulations to Dr. Ana Rita Pereira.

Ana Rita Pereira from Portugal has obtained a fellowship at University Hospital La Paz (Madrid, Spain) under the supervision of Dr. Jurado Román. The topic of her project is “Percutaneous coronary intervention (complex interventions: treatment of calcified lesions, left main stunting, treatment of bifurcations).” This EAPCI Fellowship Grant Programme is supported by Shockwave.

Ana Rita Pereira

Dr. Ana Rita Pereira

Hospital Garcia de Orta, Almada (Portugal)

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